New Hampshire residents Tuesday are voting for the presidential candidates squaring off in the first official primary of the 2016 campaign — a race some political observers are framing in a most negative fashion.

Though plenty of colorful characters continue canvassing the country in search of true believers, at least part of the electorate appears determined to write off certain White House hopefuls entirely. This purely reductive strategy, which can be summed up as the “ABCs” of any given election cycle (think “Anybody But INSERT YOUR IDEOLOGICAL NEMESIS HERE), has ensnared contenders from both parties, though certain constituencies seem to be more firmly entrenched than others.

The most fervent oppositionists have had entire lifetimes to meditate on the object of their unwavering contempt: Hillary Clinton.

This election!! is more than just your basic #ABCs #AnybodyButClinton!! It’s more than that this go-round!!

— Sarah Palin (@SarahPalin_USA_) February 1, 2016

Her rise through the ranks of the Democratic Party has kept the former first lady/New York senator/secretary of State Hillary in the public eye since the Reagan administration, providing decades for the ill will generated by her basic existence to fester into rabid disdain. The unbridled anger has manifested itself commercially — Anti-Hillary collectibles make it possible to broadcast dissatisfaction with her via in-your-face apparel or from the comfort of one’s car — as well as philosophically.

Clinton haters are legion in cyberspace, congregating on Facebook and Reddit to pick apart the would-be POTUS. (“Don’t take it literally. There are obviously people who would make worse presidents. It’s just to be catchy,” the Reddit crew, clearly hoping to drive Web traffic, explains away the cynical title of its running conversation.)

Never ones to be shut out of a rhetorical sparring match, the Twitterati continue to weigh in on all things Clinton via two invective-packed discussion threads: the leading #AnybodyButClinton rant and subordinate #AnyoneButClinton thread.

The bickering on the “AnybodyButClinton” channel predates the “AnyoneBut” venting by eight months, kicking off in August 2013 with a report about Vice President Joseph R. Biden Jr. mulling entry into the 2016 fray.

#JoeBiden Team Sows Seeds For #2016Election #POTUS https://t.co/0w9xEM4pXz Winning is simply ABC #AnybodyButClinton #Hillary #Foxnews #MSNBC — Gloom and Doom (@GloomandDoom1) August 19, 2013

The backlash against Iowa Caucus winner Sen. Ted Cruz ensued just a few months later, though back then the online bashing was prompted by the Texas Republican’s perceived coordination of the 2013 government shutdown rather than any designs on higher office.

@chrislhayes Letting a Freshman Sen from TX control our Government is like letting your Dentist perform a heart transplant. #AnybodyButCruz

— Chuck Montgomery (@ChuckMontgomer1) October 16, 2013

Since then, the movement has continued to build, invading Twitter (#AnybodyButCruz, #AnyoneButCruz) and Facebook. The virtual antagonism, however, pales in comparison to the revulsion Cruz inspires in real life.

New York Times op-ed columnist Frank Bruni railed against the freshman lawmaker in December 2015.

“The religious right already adores him, but to go the distance, he needs more support from other, less conservative Republicans, and he knows it. Expect orchestrated glimpses of a high-minded Cruz, less skunk than statesman, his sneer ceding territory to a smile,” Bruni warned.

A painfully awkward video that recently surfaced of Cruz planting what appears to be an unwanted kiss on his daughter, Caroline, during a campaign stop in the Hawkeye State hasn’t helped soften any of his purported rough edges.