As both the GOP establishment and some in the tea party have panicked over the controversy, McCaskill has been notably careful in her comments. National Democratic strategists have been all but silent on the matter.
The NRSC's tone and aggression with him is unusual and has not been the committee's modus operandi this cycle. The committee has taken a largely hands-off approach to candidate selection.
And it is not just party leaders who have castigated Akin. Rank-and-file Republicans nationwide have not been able to draft press releases quickly enough to condemn Akin. Two of the most commonly used words are "outrageous" and "offensive."
Earlier this afternoon, Missouri Sen. Roy Blunt and former Missouri Sens. John Ashcroft, Kit Bond and John Danforth, all Republicans, called for Akin to withdraw.
Akin's decision to stay in the race coincides with the morning release of a new television advertisement from the Akin campaign. Akin is using about $190,000 this week to run the ad across the state, banking on the forgiveness of voters even if he's lost that battle with establishment Republicans.
"Rape is an evil act. I used the wrong words in the wrong way, and for that I apologize," he says in the ad. He also acknowledged that "rape can lead to pregnancy."