Isakson missed out earlier this year when Sens. Tom Coburn (R-Okla.) and John Thune (R-S.D.), both also from the 2004 class of Senators, were named to the panel instead.
Also uncertain is whether conservative Sen. Jim DeMint (R-S.C.) will seek the post. DeMint is also from the 2004 class, and in 2008 the conservative Club for Growth, then under the leadership of now-Sen. Pat Toomey (R-Pa.), waged an unsuccessful campaign along with other conservative groups to get McConnell to install DeMint on the panel. At the same time, the club pushed Republican leaders to name Rep. Jeff Flake (R-Ariz.) to the Appropriations Committee. Flake at first was passed over, but he was named to Appropriations last year after the party took back the House.
Aides to McConnell declined to comment on the soon-to-be vacant Finance slot.
Former Sen. Scott Brown, R-Mass., candidate for U.S. Senate in New Hampshire, holds his hand over his heart during the singing of the national anthem as he waits to take the stage for his town hall campaign rally with Sen. John McCain at the Pinkerton Academy in Derry, N.H., on Monday, Aug. 18, 2014.