Sen. John Ensign (Nev.) will move from the National Republican Senatorial Committee to chairman of the Republican Policy Committee, while Sen. John Thune (S.D.) will replace Sen. John Cornyn (Texas) as Republican Conference Vice Chairman.
Cornyn, who originally faced a race against Sen. Norm Coleman (Minn.) to take over at the NRSC, had his path cleared when Coleman, whose re-election is still being decided, pulled out last week.
Although who will formally nominate and second McConnell is unclear, Republicans said Sen. Susan Collins (R-Maine) will nominate Kyl and second Thune to his position.
Sen. Richard Burr (R-N.C.) will nominate Thune.
Sen. Orrin Hatch (R-Utah) will nominate Cornyn, and Collins will second the nomination.
Sen. Mel Martinez (R-Fla.) will nominate Alexander, while Sen. Mike Enzi (R-Wyo.) is expected to second him.
Vice President Joe Biden waits to conduct a mock swearing-in ceremony with Sen. Brian Schatz, D-Hawaii, in the Capitol's Old Senate Chamber, December 2, 2014. Schatz was sworn in to serve the remainder of his term since he was appointed to the seat after Sen. Daniel Inouye, D-Hawaii, passed away.