Sen. John Ensign (Nev.) will move from the National Republican Senatorial Committee to chairman of the Republican Policy Committee, while Sen. John Thune (S.D.) will replace Sen. John Cornyn (Texas) as Republican Conference Vice Chairman.
Cornyn, who originally faced a race against Sen. Norm Coleman (Minn.) to take over at the NRSC, had his path cleared when Coleman, whose re-election is still being decided, pulled out last week.
Although who will formally nominate and second McConnell is unclear, Republicans said Sen. Susan Collins (R-Maine) will nominate Kyl and second Thune to his position.
Sen. Richard Burr (R-N.C.) will nominate Thune.
Sen. Orrin Hatch (R-Utah) will nominate Cornyn, and Collins will second the nomination.
Sen. Mel Martinez (R-Fla.) will nominate Alexander, while Sen. Mike Enzi (R-Wyo.) is expected to second him.